West Palm Beach Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it attempts to repair itself before the harm was done. Moses Chiropractic is always amazed at how the body takes care of itself! Moses Chiropractic sees its West Palm Beach chiropractic care as a partner of the body’s system in healing particularly when there is spine pain. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value in its ability to interrupt the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are associated with intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to its cellular level via autophagy, the natural process during which the body’s cells clean out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin enhanced autophagy and reduced the degradation of the disc’s extracellular matrix (technically indicated by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin prevents intervertebral disc degeneration by stimulating autophagy. (3) Wow. Moses Chiropractic is encouraged by this research to see just how well melatonin can perform for West Palm Beach back pain linked to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is such a common condition seen at Moses Chiropractic making positive news like this quite exciting. A recent study stated that melatonin could modify the extracellular matrix of the disc remodeling process initiated by IL-1 β. Additionally, melatonin reduced the inflammatory cell collection and decreased the release of linked inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin disrupted the IL-1B feedback loop, researchers postulated that melatonin may support the restoration process of intervertebral discs after damage has already been done. (1) Moses Chiropractic continues following the new research regarding the role inflammation performs in West Palm Beach disc degeneration and melatonin’s role in reducing it.

INFLAMMATION AND MELATONIN

The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other things is quite fitting. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by hindering the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland produces melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific effect on inflammation and disc degeneration is most interesting to Moses Chiropractic and our West Palm Beach back pain patients.

CONTACT Moses Chiropractic

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management addresses disc degeneration for relief of chronic low back pain in her patient.

Schedule your West Palm Beach chiropractic appointment with Moses Chiropractic now. We can discuss how inflammation affects your back pain and how melatonin may address the related disc degeneration.

 
Moses Chiropractic presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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